InnovationScienceTechnology

Copper Catalyst Enables Breakthrough in Chiral Piperidine Synthesis

Researchers have unveiled a novel catalytic method for synthesizing chiral piperidines, key structures in many pharmaceuticals. The approach uses copper catalysts with specialized ligands to achieve high selectivity and yields.

New Pathway to Pharmaceutical Compounds

Scientists have developed a copper-catalyzed method that enables efficient synthesis of chiral piperidines, according to research published in Nature Catalysis. The breakthrough homo-Mannich reaction uses cyclopropanols with aldimines to create these important structural motifs that are reportedly prevalent in numerous pharmaceutical compounds and natural products.

BusinessStartupsTechnology

Minor International Plans $1.5 Billion Singapore REIT Listing to Fuel Global Hotel Expansion

Bangkok-listed Minor International plans to list a hotel real estate investment trust in Singapore by early 2026, targeting $1.5 billion in fundraising. The move is part of the company’s strategic shift toward an asset-light model while capitalizing on the post-pandemic travel recovery.

Major REIT Listing Planned for 2026

Minor International, the Bangkok-listed hospitality giant controlled by billionaire William Heinecke, reportedly aims to raise approximately $1.5 billion through listing a hotel real estate investment trust in Singapore during the first quarter of 2026, according to sources familiar with the matter. The planned IPO would represent one of the region’s significant hospitality sector transactions and is designed to help reduce the company’s debt burden while funding aggressive expansion plans.

AISoftwareStartups

OpenAI Acquires Mac AI Interface Startup in Desktop Integration Push

OpenAI has acquired Software Applications Incorporated, the startup behind Sky’s natural language interface for Mac computers. The acquisition aims to accelerate ChatGPT’s integration into desktop workflows and tools people use daily.

Strategic Acquisition for Desktop AI Integration

OpenAI has acquired Software Applications Incorporated, a startup specializing in AI interfaces for Mac computers, according to reports confirming the transaction. The deal, reportedly funded through a private fund associated with CEO Sam Altman, was led by applications CEO Fidji Simo and ChatGPT head Nick Turley, though specific financial terms remain undisclosed.

InnovationScienceTechnology

Computational Breakthrough Transforms Atomic Force Microscopy into Molecular Motion Movies

Scientists have developed a computational method that translates high-speed atomic force microscopy images into precise 3D atomistic models of protein motion. The breakthrough allows researchers to create molecular movies showing functional conformational transitions previously impossible to observe at this detail level.

Revolutionary Computational Framework Bridges Imaging and Atomic Detail

Researchers have developed a groundbreaking computational framework that transforms high-speed atomic force microscopy (HS-AFM) images into detailed 3D atomistic models of protein dynamics, according to reports published in ACS Nano. The method represents a significant advancement in bridging the gap between experimental imaging and computational modeling, sources indicate.

CybersecuritySoftwareTechnology

NETSCOUT Enhances Kubernetes Monitoring with Advanced Container Visibility Solution

NETSCOUT has unveiled a breakthrough solution addressing visibility gaps in Kubernetes container environments. The new KlearSight technology captures decrypted packet data directly from the Linux kernel, enabling comprehensive monitoring without requiring encryption keys.

Breaking New Ground in Container Observability

NETSCOUT Systems has reportedly developed a significant advancement in Kubernetes monitoring technology that addresses critical visibility challenges in complex cloud environments, according to recent company announcements. The innovation comes as organizations increasingly struggle with blind spots in their multi-cluster Kubernetes deployments, where traditional monitoring approaches often fall short.

AISoftwareStartups

OpenAI Bolsters Mac Integration with Acquisition of Apple Shortcuts Team’s AI Startup

OpenAI has acquired Software Applications Incorporated, a startup founded by the original creators of Apple’s Shortcuts feature. The acquisition brings former Apple engineers who developed the Sky AI assistant to OpenAI, signaling deeper macOS integration for ChatGPT.

OpenAI Expands Mac Capabilities with Strategic Acquisition

OpenAI has acquired Software Applications Incorporated and its AI application Sky, according to reports confirmed by the company. The acquisition brings onboard a team of former Apple employees renowned for their work on Apple’s Shortcuts automation feature and the Workflow app that preceded it.

AIInnovationSoftware

OpenAI Launches Atlas Browser in Bid to Revitalize Web Navigation with AI

OpenAI has entered the browser market with Atlas, an AI-enhanced platform aiming to compete with established giants like Google Chrome. Industry analysts question whether AI capabilities can overcome user inertia in the browser space, despite OpenAI’s track record of rapid adoption with previous products.

OpenAI Expands Reach with AI-Powered Browser

OpenAI has launched Atlas, a new web browser infused with artificial intelligence capabilities, according to company announcements this week. The move represents the ChatGPT maker’s latest effort to expand its digital footprint beyond conversational AI and into daily web browsing habits. Sources indicate this positions OpenAI against browser market leader Google Chrome, which reportedly commands approximately 70% of global users according to Statcounter data.

BusinessStartupsTechnology

Rivian Announces Workforce Reduction Amid EV Tax Credit Changes

Electric vehicle manufacturer Rivian is reportedly cutting more than 600 positions, representing approximately 4.5% of its workforce. The layoffs come as the Trump Administration eliminates federal tax credits that had boosted EV sales.

Major Workforce Reduction at Electric Vehicle Maker

Electric vehicle manufacturer Rivian is planning to eliminate more than 600 positions, according to an internal memo viewed by Business Insider. Sources indicate this represents approximately 4.5% of the company’s 15,000-strong workforce and marks one of several rounds of layoffs the automaker has conducted over the past three years.

AIBusinessCybersecurity

Social Engineering and AI Fuel Unprecedented Cybersecurity Threats in 2025

Cybersecurity threats have evolved dramatically in 2025 with Clickfix attacks surging 500% and AI-powered business email compromise scams becoming increasingly sophisticated. These emerging tactics specifically target human psychology rather than technological vulnerabilities, according to new threat intelligence analysis.

Social Engineering Attacks Surge as Cybercriminals Shift Tactics

Cybersecurity threats are undergoing a significant transformation in 2025, with attackers increasingly focusing on human psychology rather than technological vulnerabilities, according to recent threat intelligence reports. Mimecast’s latest Global Threat Intelligence Report, which analyzed trillions of signals from January to September 2025, indicates that social engineering techniques and artificial intelligence abuse are becoming the weapons of choice for modern cybercriminals.

InnovationSoftwareTechnology

Microsoft PowerToys Update Resolves Theme-Switching Issues and Enhances User Control

Microsoft has rolled out PowerToys 0.95.1, addressing user complaints about automatic theme switching and introducing new scheduling options. The update also includes fixes for Command Palette, Find My Mouse, and installer stability. Users can download it via the Microsoft Store or GitHub for enhanced functionality.

PowerToys Update Tackles Theme-Switching Bugs

Microsoft has released PowerToys version 0.95.1 for Windows 11 and Windows 10 users, focusing on resolving key issues reported by the community. According to reports, this update specifically addresses problems with the Light Switch module, which enables automatic theme switching but had been causing unintended changes for some users.