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Modular Vaccine Platform Using Nanobodies Shows Broad Protection Against Multiple Respiratory Viruses

Scientists have developed a breakthrough vaccine platform using nanobody technology that can display multiple viral antigens on licensed vaccine particles. The approach demonstrated robust protection against three major respiratory viruses in animal models, potentially revolutionizing combination vaccine development.

Breakthrough in Combination Vaccine Technology

Researchers have developed a novel modular vaccine platform that uses nanobody technology to create combination vaccines protecting against multiple respiratory viruses simultaneously, according to a report published in Nature Biomedical Engineering. The approach reportedly overcomes longstanding challenges in combination vaccine development, including antigen compatibility and immunogenic balance, through what sources describe as a “plug-and-display” system.