Category: Technology

InnovationScienceTechnology

Membrane-Tethered SLP-76 Boosts CAR T Cell Efficacy Against Low-Antigen Tumors

Scientists have engineered a membrane-tethered version of the signaling molecule SLP-76 that significantly improves CAR T cell recognition of tumor cells with low antigen expression. The breakthrough addresses a major limitation in current CAR T therapies where cancer cells escape detection by downregulating target antigens. Early studies show the approach works across multiple CAR targets including CD19, CD22, and BCMA.

Breakthrough in Overcoming CAR T Cell Resistance

Researchers have developed a novel engineering approach that reportedly enables CAR T cells to recognize and eliminate tumor cells with low antigen expression, according to a recent study published in Nature Cancer. The method involves creating a membrane-tethered version of the signaling molecule SLP-76, which sources indicate could represent a significant advancement in addressing one of the major limitations of current CAR T cell therapies.

by Samuel Kim
EnergyScienceTechnology

Advanced TRISO Fuel Technology Poised to Revolutionize Nuclear Safety and Economics

New TRISO fuel technology could enable inherently safe nuclear reactors that eliminate meltdown risks. As demand for carbon-free power surges, Standard Nuclear emerges as a key player in developing domestic fuel manufacturing capabilities to reduce geopolitical dependencies.

Nuclear Safety Paradigm Shift

Recent analyses highlight a striking paradox in public perception of energy sources. Studies suggest that nearly half a million people died in the U.S. alone from complications related to pollution from coal-fired electrical plants between 1999 and 2020, yet nuclear power accidents over 74 years have claimed far fewer lives, reportedly numbering in the hundreds to thousands globally. Despite this disparity, public fear has historically favored coal over nuclear energy, though recent polling indicates shifting attitudes as carbon-free power demand grows.

by Priya Kapoor
AISemiconductorsTechnology

Nvidia Delivers $83 Billion to Shareholders Amid AI Dominance, Analysts Report

NVIDIA has reportedly returned approximately $83 billion to shareholders through dividends and stock buybacks over the last ten years. Sources indicate the company’s strong position in AI chips and substantial cash flows could lead to increased capital returns. Historical data shows the stock has experienced significant volatility during market downturns despite its strong fundamentals.

Nvidia’s Decade of Substantial Shareholder Returns

NVIDIA Corporation has reportedly returned approximately $83 billion to its investors over the past decade through dividend payments and share repurchases, according to financial analysis. Sources indicate this substantial capital return reflects the company’s strong financial performance and management’s confidence in its cash flow sustainability.

by Samuel Kim